Antibiotics & You
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Penicillins

Flucloxacillin

Skin and soft tissue infections such as cellulitisInfected woundsBoils

This medicine is in the penicillin family. Side effects like sickness or diarrhoea are not an allergy — read what a penicillin allergy actually means.

Start a diary for this antibiotic

Information follows NICE antimicrobial prescribing guidance and the BNF.

Common side effects

  • Feeling sick
  • Diarrhoea
  • Stomach discomfort

How often each one happens varies by medicine and product, so check your leaflet. Many are mild, but ask your pharmacist or doctor if they are troublesome or do not settle.

Less common side effects

  • Being sick
  • Rash
  • Joint or muscle aches

Get medical help straight away if you notice

  • Liver problems: yellow skin or eyes, dark urine, pale stools, itching — these can start weeks after stopping
  • Severe allergic reaction

Taking it safely

  • Take on an empty stomach, an hour before food or two hours after.
  • Report yellowing of the skin or eyes straight away, even after the course ends.

Report a side effect

You can report any suspected side effect to the UK Yellow Card scheme at yellowcard.mhra.gov.uk.